The network is directed and overseen by a Steering Committee

The Executive Committee and Steering Committee have primary responsibility for governance of the Network, the conduct of protocols, and the preparation of publications. The Steering Committee includes a principal investigator (PI) from each clinical center, a PI from each ancillary site, the PI from the Data Coordinating Center (DCC), and the Steering Committee Chairperson.

When a smaller committee is required to make Network decisions, the Executive Committee will convene. The Executive Committee includes a PI from each clinical center, a PI from the DCC, and the Steering Committee Chairperson. The Executive and Steering Committees meet at least three times a year, with additional meetings as needed.